Compile Data Set for Download or QSAR
Found 238 of ic50 data for polymerid = 4735,50004227,50006037
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 8nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50441210(CHEMBL2431008)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of Mycobacterium tuberculosis IspC by photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NN8PubMed
LigandPNGBDBM50528602(CHEMBL4567904)copy SMILEScopy InChI
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
LigandPNGBDBM50528593(CHEMBL4590343)copy SMILEScopy InChI
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
LigandPNGBDBM50528598(CHEMBL4474216)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 28nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMed
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMed
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMed
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of Escherichia coli DxrMore data for this Ligand-Target Pair
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50441211(CHEMBL2431007)copy SMILEScopy InChI
Affinity DataIC50: 42nMAssay Description:Inhibition of Mycobacterium tuberculosis IspC by photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NN8PubMed
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 42nMpH: 7.5Assay Description:Assays were performed in 50 mM Tris/HCl buffer, pH 7.5, containing 3 mM MgCl2 and 2 mM DTT. The concentrations of NADPH and DXP were 0.15 and 0.5 mM ...More data for this Ligand-Target Pair
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
LigandPNGBDBM50380000(CHEMBL258981)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 49nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
LigandPNGBDBM50185361((1R,2S)-2-[N-(acetyl),N-(hydroxy)aminomethyl]-cycl...)copy SMILEScopy InChI
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7N24PubMed
LigandPNGBDBM50422669(CHEMBL607359 | UK-513)copy SMILEScopy InChI
Affinity DataIC50: 54nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMed
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 58nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7N24PubMed
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMed
LigandPNGBDBM50181154(1-(3,4-dichlorophenyl)-3-(N-hydroxyformamido)propy...)copy SMILEScopy InChI
Affinity DataIC50: 59nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMed
LigandPNGBDBM50422650(CHEMBL606521)copy SMILEScopy InChI
Affinity DataIC50: 65nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMed
LigandPNGBDBM50028362(CHEMBL3341763)copy SMILEScopy InChI
Affinity DataIC50: 70nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP83RXPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measure...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant DXR expressed in Escherichia coli BL21 (DE3) using DXP as substrate and Mn2+ as cofactor preincu...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate assessed as formation of MEP measured every 5 secs for 180 secs by spectrophotome...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50028309(Fosmidomycin Sodium)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibitory activity against recombinant Trypanosoma cruzi (Trypanosoma cruzi) Trypanothione reductaseMore data for this Ligand-Target Pair
In DepthDetails
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR assessed as NADPH-dependent conversion of 1-deoxy-D-xylulose 5-phosphate to 2-C-methyl-D-erythritol 4-ph...More data for this Ligand-Target Pair
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium smegmatis (strain ATCC 700084 / mc(2...)
Universit£ de Strasbourg/CNRS

Curated by ChEMBL
LigandPNGBDBM50153713(3-(N-hydroxyformamido)propylphosphonic acid | 3-[F...)copy SMILEScopy InChI
Affinity DataIC50: 80nMAssay Description:Inhibition of Mycobacterium smegmatis DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2474BWKPubMed
LigandPNGBDBM50181152(1-(4-chlorophenyl)-3-(N-hydroxyacetamido)propylpho...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMed
LigandPNGBDBM50335484((R)-1-(4-chlorophenyl)-3-(N-hydroxyacetamido)propy...)copy SMILEScopy InChI
Affinity DataIC50: 99nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMed
LigandPNGBDBM50422666(CHEMBL607492)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration against DOXP reductoisomeraseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2VH5Q21PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50528598(CHEMBL4474216)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by phot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50441208(CHEMBL2431010)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of Mycobacterium tuberculosis IspC by photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NN8PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50528593(CHEMBL4590343)copy SMILEScopy InChI
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by phot...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
LigandPNGBDBM50335485((R)-1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)p...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XD12NVPubMed
LigandPNGBDBM50181148(1-(3,4-dichlorophenyl)-3-(N-hydroxyacetamido)propy...)copy SMILEScopy InChI
Affinity DataIC50: 119nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50441189(CHEMBL2431003)copy SMILEScopy InChI
Affinity DataIC50: 120nMAssay Description:Inhibition of Mycobacterium tuberculosis IspC by photometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JH3NN8PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50437793(CHEMBL2407193)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR using DXP as substrate measured every 5 secs for 250 secs in presence of NADPHMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2S183W1PubMed
LigandPNGBDBM50028363(CHEMBL3342259)copy SMILEScopy InChI
Affinity DataIC50: 140nMAssay Description:Inhibition of Escherichia coli M15 recombinant IspC using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KP83RXPubMed
LigandPNGBDBM50181150(3-(N-hydroxyformamido)-1-(4-methoxyphenyl)propylph...)copy SMILEScopy InChI
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FJ2GB6PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50380000(CHEMBL258981)copy SMILEScopy InChI
Affinity DataIC50: 159nMAssay Description:Inhibition of recombinant Mycobacterium tuberculosis Dxr expressed in Escherichia coli BL21 CodonPlus (DE3)-RIL cells using DOXP as substrate assesse...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2639RG9PubMed
LigandPNGBDBM50528597(CHEMBL4592986)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Escherichia coli IspC expressed in Escherichia coli M15 using 1-deoxy-D-xylulose 5-phosphate as substrate by photometric as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WW7N4ZPubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Antagonism of phenylephrine stimulated contraction of the rat isolated spleen.More data for this Ligand-Target Pair
LigandPNGBDBM50185359(2-[N-(acetyl),N-(hydroxy)aminomethyl]-cyclopropylp...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant Escherichia coli DXRMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q22F7N24PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Mycobacterium tuberculosis)
Lehrstuhl für Biochemie

Curated by ChEMBL
LigandPNGBDBM50181153(3-(N-hydroxyacetamido)propylphosphonic acid | 3-(N...)copy SMILEScopy InChI
Affinity DataIC50: 160nMAssay Description:Inhibition of Mycobacterium tuberculosis DXR assessed as reduction of 1-deoxy-D-xylulose 5-phosphate into 2-C-methyl-D-erythritol-4-phosphate measure...More data for this Ligand-Target Pair
LigandPNGBDBM50379999(CHEMBL1161784)copy SMILEScopy InChI
Affinity DataIC50: 170nMAssay Description:Antagonism of norepinephrine induced contraction of rat isolated thoracic aorta.More data for this Ligand-Target Pair
In DepthDetails
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